Melasma emulsion7/29/2023 However, a color change was detected in O/W and W/O emulsions, especially at 40☌ storage condition within 28 and 14 days, respectively. All samples complied with the microbial limits test for nonsterile pharmaceutical preparation for cutaneous products. All formulations had a-arbutin remaining higher than 90% (approximately 92%) after being stored for 60 days in all storage conditions with no significant changes in pH or viscosity. It was found that pH had no influence on the a-arbutin or formulations’ stability. For stability, at least 90% of the initial a-arbutin concentration quantified by stability-indicating high-performance liquid chromatography must be obtained. Stability was defined as no dramatic change in color, viscosity, pH, and no visible microbial growth. Cream characteristics and all aspects of product stability including physical, chemical, and microbial were investigated. The stability of the creams was studied for 60 days under three storage conditions (i.e., 2☌ to 8☌, 30☌, 40☌). Cream bases were formulated with two pH values, 4.0 and 5.5, using a hot process. Invest in our Melasma Targeted Skincare Package to achieve a brighter, more even complexion and say goodbye to hyperpigmentation caused by melasma.Abstract: Concentrated 7% w/w a-arbutin cream was formulated and evaluated using O/W and W/O emulsion bases as an extemporaneous preparation for melasma treatment. To get the best results, please note that all other skincare products currently in use must be stopped. This cream is suitable for normal, oily, and combination skin, blemish-prone skin, and stressed skin. The cream's exclusive and high concentration of biomimetic peptides helps restore the skin's natural function, leaving it soft, smooth, and moisturised. The powder adapts to any skin tone and is fragrance-free, making it suitable for all skin types, including sensitive skin.įinally, our Melasma Targeted Skincare Package includes Nexultra P Light Advanced Balancing Skin Light Emulsion, a fragrance-free cream that provides anti-inflammatory, moisturising, and repairing properties to the skin. This innovative brush-on powder offers a broad-spectrum UVA & UVB protection with 100% mineral filters that reflect UV radiation. This light and invisible day cream is suitable for normal, dry, and combination skin.įor extra protection against UV rays, we've added Nexultra UV powder - Mineral Powder Brush SPF50 UVA/UVB to the package. To complement the serum, we've included Nexultra L - Light Day Cream with Full Mineral SPF30, which helps rebalance and hydrate the skin while protecting against harmful UV rays, pollution, and free radicals. The package includes an AM serum vial (15ml) and PM serum vial (15ml) to provide a two-month supply. The serum contains a unique combination of active ingredients at the right concentration to reduce hyperpigmentation and even out skin tone. Our personalised skincare package includes Dr Sknn | Universkin Personalised Day & Night Serum P, which is customised by your doctor to tackle your skin's specific needs. It's often triggered by hormonal changes, sun exposure, and genetics, and can be difficult to treat. Melasma is a common skin condition that causes brown or grey patches on the face, particularly on the cheeks, nose, forehead, and chin. Introducing our Melasma Targeted Skincare Package, designed to tackle hyperpigmentation caused by melasma.
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